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Antihistamines are commonly used for the treatment of various allergic diseases, and can be taken in oral, nasal spray, eye drop, and injected forms.Antihistamines for Hay Fever (Allergic Rhinitis)Newer oral antihistamines, such as Xyzal (levocetirizine), Zyrtec (cetirizine), Allegra (fexofenadine), Clarinex (desloratadine) and Clarinex (loratadine), are very effective therapies for the treatment of hay fever.Although sedatives do not relieve pain in themselves, they can be a useful adjunct to analgesics in preparing patients for surgery, and are commonly given to patients before they are anaesthetized, or before other highly uncomfortable and invasive procedures like cardiac catheterization, colonoscopy or MRI.They increase tractability and compliance of children or troublesome or demanding patients.

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Due to their safety and improved effectiveness, they have largely replaced barbiturates as drugs of choice in the treatment of anxiety.

Besides those two groups of drugs, other sedatives are also used for that purpose.

Barbiturates are nonselective CNS depressants that used to be the mainstay of treatment to sedate patients or to induce and maintain sleep.

There is some overlap between the terms "sedative" and "hypnotic".

Advances in pharmacology have permitted more specific targeting of receptors, and greater selectivity of agents, which necessitates greater precision when describing these agents and their effects: Doctors often administer sedatives to patients in order to dull the patient's anxiety related to painful or anxiety-provoking procedures.

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